uneasy

"A school of fish disturbed the water."

"Before the big exam, Maria felt a strong anxiety about failing. "

"My stomachache caused me a lot of discomfort during the test. "

"He discovered penicillin largely accidentally."

"the result of a course of action;  the result of a mathematical operation"

"We are waiting the bus to arrive. "

"The new school rules are a constraint on how much time students can spend playing outside. "

"The night before his wedding was a restless one."

"The complicated instructions on the new software difficult me from completing the project on time. "

"The lightning caused thunder."

"You need to behave yourself, young lady."

"The heavy workload constrained me to work late every night last week. "